TUMORS OF THE SMALL INTESTINE

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PRIMARY MALIGNANT TUMORS OF THE SMALL INTESTINE: ANALYSIS OF 156 IRANIAN PATIENTS

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[Primary malignant tumors of the small intestine].

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The genomic landscape of small intestine neuroendocrine tumors.

Small intestine neuroendocrine tumors (SI-NETs) are the most common malignancy of the small bowel. Several clinical trials target PI3K/Akt/mTOR signaling; however, it is unknown whether these or other genes are genetically altered in these tumors. To address the underlying genetics, we analyzed 48 SI-NETs by massively parallel exome sequencing. We detected an average of 0.1 somatic single nucle...

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primary malignant tumors of the small intestine: analysis of 156 iranian patients

156 iranian patients with primary malignant tumors of the small intestine were reviewed. malignant lymphoma was the most common tumor type, comprising 128 patients (82%), followed by adenocarcinoma (22 patients, 14.1 %), leiomyosarcoma (4 patients, 2.56%) and carcinoid tumor (2 patients, 1.28%). lymphomas and adenocarcinomas were primarily located in the duodenum or jejunum, whereas leiomyosarc...

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ژورنال

عنوان ژورنال: Annals of Surgery

سال: 1934

ISSN: 0003-4932

DOI: 10.1097/00000658-193411000-00006